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quinupristin/dalfopristin will boost the amount or impact of lemborexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Avoid coadministration of lemborexant with reasonable or solid CYP3A inhibitors.quinupristin/dalfopristin will raise the level or impact of lumateperone by impacting hepatic/intestinal enz